Baker Bros. Advisors — PRAX

How Baker Bros. Advisors's position in PRAXIS PRECISION MEDICINES I changed quarter by quarter. Change badges compare each quarter to the fund's immediately-prior filing.

Quarter	Shares	Value	% of portfolio	Change
Q1 2026	1,753,198	$564,862,864	3.24%	ADD
Q4 2025	1,126,488	$332,021,073	1.94%	NEW