Baker Bros. Advisors — SION

How Baker Bros. Advisors's position in SIONNA THERAPEUTICS INC changed quarter by quarter. Change badges compare each quarter to the fund's immediately-prior filing.

Quarter	Shares	Value	% of portfolio	Change
Q1 2026	400,000	$16,036,000	0.09%	—
Q4 2025	400,000	$16,456,000	0.1%	NEW